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Acumen Pharmaceuticals Inc(ABOS.US)Thoughts post 2Q24 & a thesis revisit: cutting PT to $6 on lowered sabirnetug estimates amid class setbacks, remains Buy
UBS· 2024-08-15 11:50
报告行业投资评级 - 报告维持Acumen Pharmaceuticals Inc的买入评级,但将目标价从14美元下调至6美元 [4] 报告的核心观点 - 公司的主要管线sabirnetug在2028年有望获批上市,但由于同类竞品在欧洲市场的监管和商业化进展不及预期,公司将sabirnetug的峰值销售预测从68亿美元下调至24亿美元 [2][14] - 公司目前现金储备充足,可以支持到2027年上半年sabirnetug二期临床试验结果出炉 [11] - 公司二期临床试验enrollment进度超预期,有望提前获得结果 [11] - 整个阿尔茨海默病领域的投资者和学术界普遍情绪低迷,但公司sabirnetug的临床数据持续验证其疗效和安全性,是公司的核心投资价值 [3][14] 报告分析内容 行业整体情况 - 阿尔茨海默病市场整体规模仍然可观,但商业化基础设施建设进度远超预期,如Leqembi在获批后第四季度仅实现40百万美元的全球终端销售 [3] - 行业内大型制药公司退出和新进入的情况并存,整体投资者和学术界情绪普遍低迷 [3] - 但同时也有利好因素,如除amyloid类以外的其他疗法临床失败,有利于减少竞争压力 [3] 公司情况 - 公司目前现金储备2.81亿美元,可支持到2027年上半年二期临床试验结果出炉 [11] - 公司二期临床试验enrollment进度超预期,管理层对试验设计和结果表示乐观 [11] - 公司将一期皮下给药试验推迟至2025年一季度完成,后续计划待结果出炉后确定 [11] 估值分析 - 公司目标价从14美元下调至6美元,主要由于将sabirnetug的峰值销售预测从68亿美元下调至24亿美元 [13][14][15] - 下调主要原因是同类竞品在欧洲市场的监管和商业化进展不及预期,公司将欧洲市场的峰值渗透率从7%下调至2% [14] - 但公司临床数据持续验证,PoS从15%上调至20% [14]
Payments, Processors, & FinTech Apple announces broader developer access to NFC Secure Element within their own apps
UBS· 2024-08-15 11:49
ab 14 August 2024 Global Research and Evidence Lab First Read Payments, Processors, & FinTech NFC Secure Element within their own apps Apple announces broader developer access to Equities Americas Diversified Technology Services Timothy E. Chiodo, CFA Analyst timothy.chiodo@ubs.com +1-415-352 4500 Nik Cremo Analyst nik.cremo@ubs.com +1-415-352 6025 Chris Zhang, CFA Analyst chris.zhang@ubs.com +1-212-713 4911 Dylan Wright Analyst dylan.wright@ubs.com +1-212-713 3269 Jing Zhang Associate Analyst jing.zhang1@u ...
US Weekly RevPAR Update Slightly Better RevPAR This Week Driven by Business Travel
UBS· 2024-08-15 11:49
First Read US Weekly RevPAR Update Slightly Better RevPAR This Week Driven by Business Travel Weekly RevPAR up +2% YOY US Weekly RevPAR was up +2% YOY for August 4 - August 10 week, above last week's up +1%, with ADR up +140bps and occupancy up +40bps. ADR up +140bps was above last week's +60bps. Occupancy of up +40bps was slightly below last week's +50bps. RevPAR was up +11% vs. '19 per our calculations, broadly in line with last week's +11.5%. We estimate that ADR was up +20% vs. '19 (last week up +20%) a ...
Cruise Lines:Rehash ~ August 14, 2024
UBS· 2024-08-15 11:49
ab 14 August 2024 Global Research and Evidence Lab Cruise Lines Rehash - August 14, 2024 Equities Americas Leisure Goods & Services Robin M. Farley Analyst robin.farley@ubs.com +1-212-713 2060 Arpine Kocharyan Analyst arpine.kocharyan@ubs.com +1-212-713 2086 Alex Kivali Associate Analyst alex.kivali@ubs.com +1-212-713 3945 Alexia Tsimikas Associate Analyst alexia.tsimikas@ubs.com +1-212-713 2183 See here and here for past rehashes. This report has been prepared by UBS Securities LLC. ANALYST CERTIFICATION A ...
Upwork Inc(UPWK.US)July Web Traffic Stable from June, but Remains Sluggish
UBS· 2024-08-15 11:49
报告行业投资评级 - 报告给予Upwork Inc.的12个月评级为Neutral(中性)[1][7] 报告的核心观点 - 7月Upwork.com的月度独立访客量同比下降11%,与6月持平,但仍处于2年多来的最低水平[9][10] - 管理层已下调全年收入指引,预计下半年GMV将出现明显放缓[10] - 虽然7月数据相对于较弱的预期可能有所好转,但鉴于整体访客量趋势疲弱,目前仍难以判断指引是否过于保守[10] 行业概况 - Upwork是一家在线市场,为企业提供短期和长期项目的自由职业者服务,提供Upwork Basic、Upwork Plus、Upwork Business、Upwork Enterprise和Upwork Payroll等产品[19] 估值与风险 - 我们给予Upwork 11美元的目标价,基于12个月后的预测EBITDA 162百万美元,应用8.5倍EV/EBITDA估值[11][20] - 该估值低于Upwork当前约9.5倍的估值和13倍的一年期预测估值,反映了我们对短期GMV增长乏力的判断[11] - 主要风险包括宏观环境、自由职业市场相对较新、存在替代平台、以及人工智能的影响[21]
Dayforce Inc(DAY.US)2024 Boost amid $500m New Buyback = Buy
UBS· 2024-08-15 11:49
Global Research and Evidence Lab 14 August 2024 Dayforce Inc. 2024 Boost amid $500m New Buyback = Buy Non-deal road show offers a glimpse at a Special Software Story We recently hosted Dayforce CEO David Ossip, CFO Jeremy Johnson as well as multiple members from investor relations. We continue to have substantial confidence in our thesis as we believe DAY stock is poised to outperform on cloud revenue remix + improving free cash flow conversion—we believe recent underperformance is mostly due to risk-off se ...
Fiverr International Ltd(FVRR.US)July Web Traffic Data Remains Soft
UBS· 2024-08-15 11:49
报告行业投资评级 Fiverr International Ltd的12个月评级为Neutral(CBE)。[30] 报告的核心观点 1) 根据UBS Evidence Lab的网络流量监测数据,Fiverr.com的月度独立访客量在7月同比下降17%,较6月的15%下降有所加剧。这是连续第二个月呈现恶化趋势,此前自2023年末网络流量同比数据一直在改善。[2][3] 2) 管理层在7月下旬提供的第三季度收入指引已经考虑了上述较弱的趋势。Fiverr表示,6月份看到的放缓将持续到第三季度。分析师和共识预测第三季度GMV同比下降4%,略差于第二季度的3%下降。[3] 3) 分析师认为,7月网络流量的恶化已经反映在当前预测中,但8-9月的走势将很重要。[3] 根据报告目录的总结 网络流量数据 - 7月Fiverr.com的月度独立访客量同比下降17%,较6月的15%下降有所加剧。这是连续第二个月呈现恶化趋势。[2] GMV影响 - 管理层预计第三季度GMV同比下降4%,略差于第二季度的3%下降。[3] - 分析师认为7月网络流量恶化已经反映在当前预测中,但8-9月的走势将很重要。[3] 估值 - 分析师给出27美元的目标价,基于应用9倍NTM EV/EBITDA乘数得出。这一乘数低于Fiverr当前11倍的一年期估值,反映了分析师对近期GMV波动性的担忧。[4][17]
LatAm Transport and Capital Goods Daily Take~Off: ERJ, TUPY, AZUL, COPA, RAIL
UBS· 2024-08-15 11:49
Global Research and Evidence Lab 14 August 2024 LatAm Transport and Capital Goods Daily Take-Off: ERJ, TUPY, AZUL, COPA, RAIL ERJ: LATAM discussing up to 30 E2 Jets According to Aeroin, the Minister of Ports and Airports, Mr. Silvio Costa Filho, pointed out that LATAM is in negotiations to acquire jets from the Brazilian manufacturer. Moreover, the article states that LATAM expects to grow more than 10% in the next three years and is considering buying 30 planes. Nonetheless, the CEO of LATAM Brazil, Mr. Je ...
Ibotta Inc(IBTA.US)2Q24 EPS Recap~Clean up on aisle two
UBS· 2024-08-15 11:48
报告行业投资评级 - 报告给予Ibotta Inc的评级为Buy [4] 报告的核心观点 积极因素 - Instacart合作伙伴关系有望带来6%的FY25收入增长 [2] - 第三方零售合作伙伴关系是报告看好Ibotta的原因 [2] - 第三方赎回业务仍处于早期阶段,长期前景乐观 [2] 负面因素 - 广告收入疲软限制了收入和EBITDA的上行空间 [2] - 业绩波动性高于预期,需要降低EBITDA估值倍数 [2] 分部业务总结 第三方赎回业务 - 第三方赎回收入占比提升对毛利率有负面影响 [3] - 第三方赎回业务净增用户超预期,沃尔玛表现领先 [2][14] - 第三方赎回业务收入增长强劲,同比增长52.1% [14] 直接面向消费者(DTC)赎回业务 - DTC赎回收入同比下降25% [14] 其他收入 - 其他收入同比下降26.9% [15] 财务表现总结 - 总收入同比增长13.6%,超出预期 [15] - 毛利率为87.2%,较上年同期提升0.7个百分点 [16] - 销售及营销费用占比较高,达56.5% [16][17] - 调整后EBITDA同比增长11.6%,达到28.7%的利润率 [21] - 自由现金流大幅增长,达到32.7百万美元 [21][22]
US Healthcare:A Look at Today’s Stock Movers, News & Key Data
UBS· 2024-08-15 11:48
Global Research and Evidence Lab 14 August 2024 Equities Americas Healthcare Kevin Caliendo Analyst kevin.caliendo@ubs.com +1-212-713 3630 AJ Rice Analyst aj.rice@ubs.com. +1-212-713 4299 Christopher Mercado, CFA Associate Analyst christopher.mercado@ubs.com +1-212-713 1430 Andrea Alfonso Analyst andrea.alfonso@ubs.com +1-212-713 1342 Dylan Finley Associate Analyst dylan.finley@ubs.com +1-212-713-4880 US Healthcare A Look at Today's Stock Movers, News & Key Data What We Thought Was Interesting Today Today w ...