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Atara Biotherapeutics Inc. (ATRA.US) 2Q EPS: CEO transition; First CD19 oncology data now in 1Q25, with autoimmune to follow
Goldman Sachs· 2024-08-14 10:49
报告行业投资评级 Atara Biotherapeutics Inc. (ATRA)的12个月目标价为10美元,基于100%的折现现金流估值(加权平均资本成本18%,终端增长率3%)。[17] 报告的核心观点 1) Atara Biotherapeutics公司宣布CEO过渡,Cokey Nguyen将接替Pascal Touchon于9月9日生效[1] 2) 公司推迟了首个ATA3219(同种异体CD19 CAR T)在复发/难治性B细胞非霍奇金淋巴瘤中的1期数据发布时间,从原计划的2024年第四季度推迟至2025年第一季度,原因是患者入组较慢[1] 3) 公司计划将ATA3219拓展至自身免疫性疾病,包括在2024年第四季度启动1期lupus肾炎试验,并在2025年中期获得首批数据[11][12] 4) 公司还计划在2024年第四季度启动1期严重系统性红斑狼疮(SLE)试验,不需要淋巴细胞清除,并在2025年中期获得首批数据[12] 5) 公司最近发表的临床前数据显示,ATA3219 CAR T细胞可以完全清除SLE或多发性硬化症患者外周血单核细胞,同时释放较低水平的促炎细胞因子,保持与自体CAR T相当的细胞毒性功能,可能带来更好的安全性和耐受性[13] 财务数据总结 1) 公司2024年第二季度实现每股亏损3.10美元,好于高盛和VisibleAlpha预期的每股亏损4.94美元和3.19美元[14] 2) 2024年第二季度研发费用为3330万美元,低于高盛和VisibleAlpha预期的3910万美元和3880万美元[14] 3) 2024年第二季度销售及一般管理费用为890万美元,低于高盛和VisibleAlpha预期的940万美元和950万美元[14] 4) 截至2024年第二季度末,公司现金、现金等价物和投资总额为3530万美元,预计可维持至2027年[15]
Americas Advisors: Weekly M&A activity as of 08.13.2024
Goldman Sachs· 2024-08-14 10:49
13 August 2024 | 9:10AM EDT Americas Advisors: Weekly M&A activity as of 08.13.2024. Please find below summary tables to highlight weekly M&A trends for the independent advisors, bulge bracket firms, independent investment banks and mid-cap brokers. James Yaro +1(212)902-1913 | iames.e.varo@gs.com Goldman Sachs & Co. LLC Richard Ramsden +1(212)357-9981 richard.ramsden@gs.com Goldman Sachs & Co. LLC Songqing Jiang +1(212)934-0308 songqing.jang@gs.com Goldman Sachs & Co. LLC Ishan Rai, CFA +1(332)245-7603 / i ...
Asia~Pacific Portfolio Strategy: Asian equity market daily update
Goldman Sachs· 2024-08-14 10:49
13 August 2024 | 8:31 PM SGT Asia-Pacific Portfolio Strategy: Asian equity market daily update: The MXAPJ Index was flat today. Indonesia and Philippines markets outperformed, while India and Australia markets underperformed. Within MXAPJ sectors, Info Tech and Comm Serv led while Health Care and Materials lagged. MSCI Japan rose 3.1% today. For a detailed analysis, please see Weathering summer storms, August 7, 2024. Exhibit 1: The MXAPJ index has gained 5.2% YTD after gaining 5% in 2023, particularly led ...
Amotiv Ltd. (AOV.US): FY24 First Take: Result in~line with May guidance; Buy
Goldman Sachs· 2024-08-14 10:49
报告行业投资评级 - 报告给予Amotiv Ltd.(AOV.AX)公司"Buy"评级 [15] 报告的核心观点 - 公司FY24年业绩基本符合5月份的指引 [3] - 照明业务(+7.3%有机增长,+13.3%含收购)抵消了4WD业务的持续疲软 [4] - 公司现金流转换率达93%,杠杆降至1.6倍 [5] 行业分部总结 4WD & Trailering - 收入增长5%,但利润下降2% [13] - 新西兰和房车市场疲软将持续至FY25年 [7] Lighting, Power & Electrical - 收入增长13.3%,利润增长3% [13] - 澳大利亚市场增长较慢,但非澳大利亚市场增长良好 [7] Powertrain & Undercar - 收入增长6%,利润增长2% [13] - 车库业务活动水平无重大变化 [7] 展望 - 预计FY25年收入和利润将进一步增长 [8] - FY25年公司成本预计为14亿澳元,资本支出预计为25亿澳元 [8] - 公司将在10月21日的年度股东大会上提供更新 [8]
Allos SA (ALOS3.SA)2Q24 First Take:Improving Fundamentals; Income Statement Within Expectations
Goldman Sachs· 2024-08-14 10:49
13 August 2024 | 10:10PM BRT Allos SA (ALOS3.SA): 2024 First Take:Improving Fundamentals; Income Statement Within Expectations Jorel Guilloty +55(11)3372-3522 jorel.quilloty@as.com Goldman Sachs do Brasil CTVM S.A. Our take: We expect Allos 2024 results to have a muted impact on shares. Net revenue and NOI came within expectations, while property EBITDA and FFO came slightly ahead driven by better SG&A. Fundamentals generally saw an improvement with occupancy rising 60 bps y/y to 96.3%. Occupancy cost saw a ...
Americas Healthcare:Biotechnology,Boston Biotech Bus Tour~Day 1 takeaways
Goldman Sachs· 2024-08-14 10:49
13 August 2024 | 5:49AM EDT Americas Healthcare: Biotechnology: Boston Biotech Bus Tour - Day 1 takeaways We met with the management teams from LNTH, BPMC, KYMR, and RYTM during Day 1 of our Boston biotechnology bus tour. We offer our detailed takeaways below. Takeaways Lantheus Holdings (LNTH, Not Covered) We hosted Brian Markison (CEO), Paul Blanchfield (President), and Robert Marshall (CFO), as well as representatives of the company's investor relations team during our 2024 Boston Biotech Bus Tour. The c ...
Americas Restaurants: SBUX appoints current CEO of CMG as new Chairman/CEO
Goldman Sachs· 2024-08-14 10:49
13 August 2024 | 9:27AM EDT Americas Restaurants: SBUX appoints current CEO of CMG as new Chairman/CEO This morning, SBUX announced that Brian Niccol has been appointed chairman and chief executive officer, with the current CEO/chairman Laxman Narasimhan stepping down effective immediately. Mr. Niccol will join the company on September 9, with current CFO Rachel Ruggeri serving as interim CEO until then. CMG's Board of Directors has appointed Scott Boatwright, Chief Operating Officer, as Interim CEO. SBUX: ...
Americas Energy Key learnings from earnings season that support The Future of Utilities Capex; Buy SRE, PWR
Goldman Sachs· 2024-08-14 10:48
13 August 2024 | 7:45PM EDT Americas Energy Key learnings from earnings season that support The Future of Utilities Capex; Buy SRE, PWR The Future of Utilities Capex Explore > With second quarter earnings season now behind us, we reflect on key learnings that support The Future of Utilities Capex, our constructive view on Utilities, and our Buy rating on Quanta Services (PWR). We believe commentary from utilities continues to point to positive capital spending revisions as we look to the Fall and early 2025 ...
Americas Agriculture: Proposed changes in LCFS
Goldman Sachs· 2024-08-14 10:48
13 August 2024 | 11:07AM EDT Americas Agriculture: Proposed changes in LCFS Late Monday (8/12), the California Air Resources Board (CARB) proposed amendments to the Low Carbon Fuel Standard (LCFS), subject to a public hearing & vote on November 8th. This follows prior proposal amendments issued in December 2023 that had been scheduled for hearing & vote in February 2024 that was ultimately postponed. Key highlights of proposed changes 1) 9% step-down in 2025 CI reduction. CARB is proposing to modify the nea ...
GOAL:Asset Allocation
Goldman Sachs· 2024-08-13 18:26
报告行业投资评级 - 报告对MSCI Asia Pac ex Japan、STOXX Europe 600、S&P 500和TOPIX等主要股票指数维持中性3个月评级,但对12个月持中性偏积极的评级 [8] - 报告对美国、欧元区、英国和日本等主要国家10年期国债维持中性评级 [8] - 报告对美国投资级债券(Bloomberg Barclays US IG)维持中性评级,对美国高收益债券(Bloomberg Barclays US HY)和欧元区高收益债券(BAML EUR HY)维持中性偏低评级,对新兴市场债券(JP Morgan EMBI Div.)维持中性评级 [8][9] - 报告对大宗商品(WTI原油、布伦特原油、铜、黄金)维持中性3个月评级,12个月评级为中性偏积极 [8][9] 报告的核心观点 宏观经济 - 全球经济增长和通胀下降,美国增长强劲 [12] - 我们的经济周期指标显示全球经济处于"早期"后期周期位置 [24] - 股票在后期周期表现通常优于平常,尤其是在没有衰退的情况下 [26][27] 资产估值 - 股票和信用债券估值最近有所下降,而债券收益率有所上涨 [28][29] - 投资者情绪和头寸已从极度乐观的水平有所回落 [31][35][36] - 当前风险偏好指标处于历史较低水平,表明风险资产的上行空间大于下行风险 [39][40][41][42][43][44][45][46][49] 投资策略 - 在当前风险偏好较低的环境下,我们倾向于偏好防御性头寸和选择性跨资产对冲 [288][289][290][291] - 我们认为美联储降息周期有利于股票表现,但前提是经济增长良好 [55][59][60][61][62][63] - 我们认为增长动力正在取代货币政策成为风险偏好的主要驱动因素 [65][66][67][68][69][70] 行业分类总结 股票 - 我们维持对主要股指的中性3个月评级,但对12个月持中性偏积极评级 [8] - 在后期周期环境下,股票通常表现优于平常,尤其是在没有衰退的情况下 [26][27] - 我们认为增长动力正在取代货币政策成为风险偏好的主要驱动因素 [65][66][67][68][69][70] 债券 - 我们维持对主要国家10年期国债的中性评级 [8] - 我们对美国投资级债券维持中性评级,对美国高收益债券和欧元区高收益债券维持中性偏低评级,对新兴市场债券维持中性评级 [8][9] - 我们认为美联储降息周期有利于债券表现,但前提是经济增长良好 [55][59][60][61][62][63] 大宗商品 - 我们维持对大宗商品(原油、铜、黄金)的中性3个月评级,12个月评级为中性偏积极 [8][9] - 我们认为大宗商品在后期周期和高通胀环境下通常表现优于60/40投资组合 [116][153][154][155][156][157][158][159]