FDA Accepts Bayer's Application for Label Expansion of Nubeqa
ZACKS· 2024-11-23 03:41
关于拜耳公司药品相关情况 - 拜耳公司的Nubeqa(darolutamide)补充新药申请(sNDA)被FDA接受,寻求将Nubeqa与雄激素剥夺疗法(ADT)联合用于治疗转移性激素敏感性前列腺癌(mHSPC)患者的标签扩展[1]。 - Nubeqa是一种雄激素受体抑制剂(ARi),sNDA基于ARANOTE研究的积极结果,Nubeqa加ADT相比安慰剂加ADT显著降低转移mHSPC患者进展或死亡风险[3]。 - Nubeqa目前用于治疗成人mHSPC患者(与多西他赛联合)以及非转移性去势抵抗性前列腺癌(nmCRPC)患者,FDA对sNDA的潜在批准将扩大其在mHSPC患者中的适应症[4]。 - 拜耳正在广泛的开发计划中评估darolutamide在前列腺癌各个阶段的情况,包括ARASTEP试验和DASL - HiCaP试验[5][6]。 - Nubeqa是拜耳的顶级药物之一,2024年前9个月销售额超过10亿欧元,标签扩展有望进一步促进销售[7]。 - 拜耳与Cytokinetics(CYTK)就aficamten在日本的独家开发和商业化达成合作许可协议,aficamten正在被评估用于治疗肥厚性心肌病(HCM)患者,拜耳计划在日本阻塞性HCM患者中进行III期研究[8]。 - 拜耳从BridgeBio获得acoramidis在欧洲的营销权,FDA已为acoramidis设定2024年11月29日为目标行动日期,同时拜耳也向EMA提交了elinzanetant的营销授权申请(MAA),FDA接受了elinzanetant的新药申请(NDA),二者都寻求用于治疗与更年期或辅助内分泌治疗相关的中度至重度血管舒缩症状(VMS)[9][10]。 拜耳公司股票相关情况 - 今年迄今为止,拜耳公司股价下跌44.9%,而行业增长4.8%[2]。 关于辉瑞公司相关情况 - 辉瑞(PFE)目前的扎克斯排名为2(买入),过去60天,其2024年每股收益预期从2.62美元升至2.91美元,2025年从2.85美元升至2.92美元,今年迄今为止股价下跌12.2%,且在过去四个季度中每个季度的收益都超出预期,平均惊喜幅度为74.50%[11][12]。
Novartis Raises Sales Outlook for Mid-Term, Acquires Kate Therapeutics
ZACKS· 2024-11-23 03:41
Novartis (NVS) announced that it has increased its sales guidance for the mid-term. The company now expects total sales to witness a compound annual growth rate (CAGR) of 6% during 2023-2028 compared with the previous estimate of 5%.The rise in guidance was due to the strong momentum of NVS’ key drugs and its upcoming launches.Shares of Novartis have risen 4% year to date compared with the industry’s growth of 4.8%.Image Source: Zacks Investment ResearchNVS Raises Mid-Term OutlookFor 2024-2029, sales are ex ...
Navigating Risks: Why I'm Still Bullish On Google Stock
Seeking Alpha· 2024-11-23 03:33
公司研究 - 在第三季度财报之前对谷歌(NASDAQ: GOOGL)(NASDAQ: GOOG)进行分析认为其增长前景估值吸引力等方面值得看好尽管存在AI和监管风险 [1] 分析师相关 - 是股票研究分析师在金融市场有广泛职业经历覆盖巴西和全球股票为价值投资者主要进行基本面分析关注有增长潜力的被低估股票与D.M. Martins Research有关 [2] - 分析师无文中提及公司的股票期权或类似衍生品头寸但可能在未来72小时内通过购买股票或看涨期权等在谷歌建立多头头寸文章为自己所写表达自己观点未从除Seeking Alpha外获取报酬与文中提及股票的公司无业务关系 [3]
Why NuScale Power Stock Jumped 28% to an All-Time High This Week
The Motley Fool· 2024-11-23 03:33
公司股价表现 - NuScale Power公司股价本周飙升28%至每股29.52美元的历史新高[1] - 11月该公司股价已大幅上涨50%10月已上涨65%[1] 公司业务及潜力 - 公司正在建造可扩展的小型模块化反应堆(SMRs)以提供低成本可靠无碳电力SMRs比传统核反应堆小很多且可建于不适合传统核反应堆的地点[2] - 公司的“VYOGR”SMR工厂商业化可能仍需数年[4] - 公司已获得美国能源部(DOE)的一些成本分摊奖励其SMR设计是首个获得美国核管理委员会认证的设计[4] 行业发展背景 - 美国白宫上周宣布打算到2050年将美国核能产量至少提高三倍包括支持小型模块化反应堆(SMRs)的发展[1] - 当选总统唐纳德·特朗普提名的下一任能源部(DOE)部长克里斯·赖特是化石燃料的坚定支持者但核能行业仍应蓬勃发展因为核能得到了共和党和民主党的支持[3] 公司股票性质 - SMRs和NuScale Power有坚实的潜力但前提是技术得到验证且可行NuScale Power股票仍然是一种投机性投资[5]
Miller Industries: The Meteoric Rise Continues
Seeking Alpha· 2024-11-23 03:30
Like every investor, I'm bound to have my winners and my losers. But one company that I have called quite well in recent years has been Miller Industries (NYSE: MLR ). For those who aren't familiar with the business, it operatesCrude Value Insights offers you an investing service and community focused on oil and natural gas. We focus on cash flow and the companies that generate it, leading to value and growth prospects with real potential.Subscribers get to use a 50+ stock model account, in-depth cash flow ...
Why Tesla Stock Ended the Week on a High Note
The Motley Fool· 2024-11-23 03:29
Tesla (TSLA 4.14%) shares have been on a roll in recent weeks. The stock has soared by more than 60% in the last month and that surge continued Friday. Tesla shares were higher by 3.7% as of 1:45 p.m. ET. That brings year-to-date gains to about 42%.Much of the recent euphoria has been related to CEO Elon Musk and his relationship with President-elect Donald Trump. But the stock's momentum may have also gotten a boost after the latest European electric vehicle (EV) sales numbers were published yesterday.EV s ...
Berry Corporation Addresses Its Debt Maturities With A High Interest Rate Term Loan
Seeking Alpha· 2024-11-23 03:27
We are currently offering a free two-week trial to Distressed Value Investing . Join our community to receive exclusive research about various companies and other opportunities along with full access to my portfolio of historic research that now includes over 1,000 reports on over 100 companies.Berry Corporation (NASDAQ: BRY ) has entered into an agreement for a new term loan that will address its near-term debt maturity issues and potentially push its next debt maturity out to 2029 (with extensions).Aaron ...
S&P 500 Moves Higher; Intuit Shares Fall Following Q1 Results
Benzinga· 2024-11-23 03:18
U.S. stocks traded higher toward the end of trading, with the Dow Jones index gaining by more than 350 points on Friday.The Dow traded up 0.82% to 44,228.50 while the NASDAQ rose 0.14% to 18,998.27. The S&P 500 also rose, gaining, 0.31% to 5,966.91.Check This Out: Top 3 Materials Stocks That Could Blast Off In NovemberLeading and Lagging SectorsConsumer staples shares rose by 1.5% on Friday.In trading on Friday, communication services shares fell by 0.6%.Top HeadlineShares of Intuit Inc INTU fell over 5% on ...
Essential Properties: Time To Consider Rotation Into More Attractive REITs
Seeking Alpha· 2024-11-23 03:15
Analyst’s Disclosure: I/we have a beneficial long position in the shares of EPRT; O either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article. While this article may sound like financial advice, please observe that the author is not a CFA or in any way licensed to give financial ad ...
Amazon tries again, with another $4 billion, to get Anthropic to use its AI chips rather than Nvidia GPUs
Business Insider· 2024-11-23 03:09
亚马逊与Anthropic投资合作相关 - 亚马逊周五宣布再向AI初创公司Anthropic投资40亿美元使总投资达80亿美元 [1][2] - 作为回报Anthropic将使用AWS作为主要云与训练伙伴并助力亚马逊设计芯片及构建AI模型开发平台 [3] - 此次投资是亚马逊对英伟达的正面冲击英伟达股票周五下跌超3% [3] Anthropic对亚马逊芯片使用态度相关 - Anthropic首席执行官此前表示使用英伟达也使用谷歌和亚马逊的定制芯片不同芯片有不同权衡 [5] - 有报道称Anthropic更倾向于使用英伟达GPU而非亚马逊AI芯片此次投资谈判重点是让Anthropic更多使用亚马逊产品 [6] - 获得40亿美元后Anthropic与亚马逊在Neuron软件上合作可能表明其更致力于使用和改进亚马逊芯片 [7][9] 亚马逊AI芯片相关 - 亚马逊2020年推出Trainium和Inferentia芯片目的是减少对英伟达依赖并降低人工智能时代云计算成本 [12] - 亚马逊CEO称客户在实施规模扩大时会发现AI成本高所以投资定制芯片且下一代Trainium 2芯片正在增加产量 [13][16] - 像许多竞争对手一样亚马逊发现打破行业对英伟达的偏好很难有分析师称未发现有公司大规模使用亚马逊芯片 [14]