H XENON CORPORATE OVERVIEW M A RC H 2 0 2 2 NASDAQ: XENE www.xenon-pharma.com Forward Looking Statement/Safe Harbor This slide presentation and the accompanying oral commentary contain forward-looking statements that involve risks, uncertainties and assumptions. If the risks or uncertainties ever materialize or the assumptions prove incorrect, our results may differ materially from those expressed or implied by such forward-looking statements. All statements other than statements of historical fact could be ...

AES 2021 Symposium Summary of Results from the "X-TOLE" Study FRIDAY, DECEMBER 3, 2021 NASDAQ: XENE www.xenon-pharma.com XEN1101 Next-Gen KV7 Channel Opener ▪ Only-in-class KV7 potassium channel modulator to treat adult focal seizures ▪ Novel MOA for rational polypharmacy ▪ Designed to address limitations of first-gen KV7 modulator, ezogabine • Higher in vitro and in vivo potency • PK TID → QD • Lacks the chemical properties that could form pigmented dimers ▪ Improved seizure reduction ▪ Potential to treat ...

AES 2021 Symposium Summary of Results from the "X-TOLE" Study FRIDAY, DECEMBER 3, 2021 NASDAQ: XENE www.xenon-pharma.com XEN1101 Next-Gen KV7 Channel Opener ▪ Only-in-class KV7 potassium channel modulator to treat adult focal seizures ▪ Novel MOA for rational polypharmacy ▪ Designed to address limitations of first-gen KV7 modulator, ezogabine • Higher in vitro and in vivo potency • PK TID → QD • Lacks the chemical properties that could form pigmented dimers ▪ Improved seizure reduction ▪ Potential to treat ...

将 XENON | SLIDE 1 Corporate Presentation December 2019 NASDAQ: XENE | www.xenon-pharma.com Forward Looking Statement/Safe Harbor This presentation and the accompanying oral commentary contain forward-looking statements that involve risks, uncertainties and assumptions. If the risks or uncertainties ever materialize or the assumptions prove incorrect, our results may differ materially from those expressed or implied by such forwardlooking statements. All statements other than statements of historical fact co ...