公司潜在风险 - 公司可能无法成功实施商业策略[8] - 公司历史上存在净亏损，可能无法实现或维持盈利[8] - 公司可能无法成功商业化微生物蛋白生产平台或其他技术[10] - 如果竞争对手比公司的产品候选品更快地开发技术和产品，并更有效地市场推广，公司的商业机会将减少或消失[11] - 公司可能需要未来大量额外资本来支持业务[13] 技术优势 - 公司的技术使得生产的蛋白质具有高纯度，无需去除病毒或内毒素，生产效率高[39] - C1细胞线的稳定性和正确折叠的单克隆抗体（mAbs）与CHO生产的mAbs具有相似的结合、中和和其他特性[40] - C1细胞线的生产速度比CHO细胞快30天，生产成本低，节省时间和金钱[41] - 昆虫细胞（即杆状病毒）提供蛋白表达，后转录修饰等优点，易于扩展规模，并且适应高密度悬浮培养，用于大规模表达[45] 市场前景 - 公司继续评估扩展C1细胞蛋白生产平台应用的潜在机会，目前专注于重点市场：重组疫苗和药物、新创新生物治疗、生物仿制药/生物改进剂非糖基化/糖基化蛋白市场、药物配方、研究诊断和试剂、食品、健康和健康替代蛋白[48] - 公司认为生物制药行业可以从一种安全、高效、可靠且具有成本效益的创新蛋白生产平台中受益。我们相信我们的C1细胞蛋白生产平台有潜力成为CHO、杆状病毒和其他传统表达系统的替代品，用于生产疫苗、治疗药物、诊断、替代食品、营养和健康以及其他生物产品[49]

Exhibit 99.1 DYADIC REPORTS 2023 FULL YEAR RESULTS AND RECENT COMPANY PROGRESS ● Closed a $6.0 million convertible note in a private placement, with a conversion price of $1.79 and no warrants ● Reported positive topline data from First-In-Human Phase 1 trial demonstrated clinical safety and antibody response for DYAI-100 a recombinant protein receptor binding domain (RBD) booster vaccine candidate for protection against COVID-19 infection ● Entered into several fully funded vaccine and antibody projects co ...

公司介绍 - Dyadic International, Inc.是一家全球生物技术公司，专注于构建创新的微生物平台，以满足全球蛋白生物制品需求的增长和人类和动物健康领域对有效、负担得起和可获得的生物制药产品的未满足需求[6] 展示活动 - Dyadic将在Future Food-Tech“从农场到餐桌的创新与投资”活动中展示其Dapibus™微生物表达系统，并提供其替代蛋白质业务部门正在开发的产品进展更新[2] 合作关系 - Dyadic最近与Biftek, Inc.达成了共同营销合作伙伴关系，旨在推广Biftek的专利待定的无动物生长培养基补充剂，以降低昂贵培养基组分（如牛血清白蛋白）的成本[3]

JUPITER, Fla., March 14, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. (“Dyadic”, “we”, “us”, “our”, or the “Company”) (NASDAQ: DYAI), a global biotechnology company focused building innovative microbial protein production platforms to address the growing demand for global protein bioproduction utilizing its advanced microbial platforms to develop and manufacture prophylactic, therapeutic, and nutritional biopharmaceutical products for human and animal health and wellness, today announced that it will ...

JUPITER, Fla., March 14, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. (“Dyadic”, “we”, “us”, “our”, or the “Company”) (NASDAQ: DYAI), a global biotechnology company focused building innovative microbial protein production platforms to address the growing demand for global protein bioproduction utilizing its advanced microbial platforms to develop and manufacture prophylactic, therapeutic, and nutritional biopharmaceutical products for human and animal health and wellness, today announced that it will ...

JUNIPER, Fla., March 11, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. ("Dyadic" or the "Company") (NASDAQ:DYAI), a global biotechnology company focused on building innovative microbial protein production platforms to address the growing demand for global protein bioproduction utilizing its advanced microbial platforms to develop and manufacture prophylactic, therapeutic, and nutritional biopharmaceutical products for human and animal health and wellness, announced today that it entered into a securit ...

JUPITER, Fla. and BUNNIK, the Netherlands, Feb. 28, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. ("Dyadic", "we", "us", "our", or the "Company") (NASDAQ:DYAI), a global biotechnology company focused on applying its innovative microbial protein production platforms to address the growing demand for global protein bioproduction and unmet clinical needs for effective, affordable and accessible biopharmaceutical products for human and animal health today announced its Dutch subsidiary, Dyadic Nederland B ...

JUPITER, Fla. and LELAND, N.C., Feb. 13, 2024 (GLOBE NEWSWIRE) -- Dyadic International Inc. ("Dyadic", or the "Company") (NASDAQ:DYAI) and Cygnus Technologies®, part of Maravai LifeSciences® (NASDAQ:MRVI), announced today a strategic partnership for the quantification of Host Cell Proteins ("HCP") from the proprietary and patented C1-cells filamentous fungus Thermothelomyces heterothallica, (formerly Myceliophthora thermophila). Under the terms of the partnership agreement, Cygnus has developed the C1 HCP E ...

JUPITER, Fla., Feb. 06, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. ("Dyadic", "we", "us", "our", or the "Company") (NASDAQ:DYAI), a global biotechnology company announced it has signed a fully funded evaluation agreement including commercial option with an undisclosed leading global biopharmaceutical company to design and produce recombinant proteins using Dyadic's C1 filamentous fungal based microbial protein production platform. Under the agreement, research and development activities will be fun ...

JUPITER, Fla., Feb. 01, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. ("Dyadic", or the "Company") (NASDAQ:DYAI), a global biotechnology company focused on building innovative microbial platforms to address the growing demand for global protein bioproduction and unmet clinical needs for effective, affordable and accessible biopharmaceutical products for human and animal health, and alternative proteins for food, nutrition and wellness, today announced that its management will be attending the followin ...