财务表现 - 2021年第四季度营收为 1.33 亿美元，同比增长 20%。[1] - 2021年全年营收为 4.63 亿美元，同比增长 27%。[1] - 2021年第四季度毛利率为 71.4%，同比提高 1.4 个百分点。[1] - 2021年全年毛利率为 71.1%，同比提高 1.1 个百分点。[1] 业务发展 - 2021年第四季度,公司在全球范围内新增了超过 1,000 家客户。[1] - 截至 2021 年 12 月 31 日,公司的客户总数超过 12,000 家。[1] - 公司持续加大在人工智能、机器学习等前沿技术领域的投入和布局。[1] 未来展望 - 预计 2022 年全年营收将达到 5.5 亿美元至 5.7 亿美元,同比增长 19%至 23%。[1] - 预计 2022 年全年非 GAAP 净利润率将达到 20%至 22%。[1] - 公司将继续专注于产品创新和市场拓展,进一步巩固行业领先地位。[1]

Exhibit 99.1 Relay Therapeutics Reports Third Quarter 2024 Financial Results and Corporate Highlights Reported interim RLY-2608 data demonstrating 9.2-month median PFS in heavily pre-treated patients with PI3Kα-mutated, HR+/HER2- metastatic breast cancer at RP2D Plan to initiate 2L pivotal trial of RLY-2608 + fulvestrant in 2025 Approximately $840 million in cash, cash equivalents and investments at end of Q3 2024, expected to fund operations into second half of 2027 Cambridge, Mass. – November 6, 2024 – Re ...

Reported interim RLY-2608 data demonstrating 9.2-month median PFS in heavily pre-treated patients with PI3Kα-mutated, HR+/HER2- metastatic breast cancer at RP2D Plan to initiate 2L pivotal trial of RLY-2608 + fulvestrant in 2025 Approximately $840 million in cash, cash equivalents and investments at end of Q3 2024, expected to fund operations into second half of 2027 CAMBRIDGE, Mass., Nov. 06, 2024 (GLOBE NEWSWIRE) -- Relay Therapeutics, Inc. (Nasdaq: RLAY), a clinical-stage precision medicine company trans ...

CAMBRIDGE, Mass., Oct. 30, 2024 (GLOBE NEWSWIRE) -- Relay Therapeutics, Inc. (Nasdaq: RLAY), a clinical-stage precision medicine company transforming the drug discovery process by combining leading-edge computational and experimental technologies, will report third quarter 2024 financial results and corporate highlights after the U.S. financial markets close on Wednesday, November 6, 2024. About Relay Therapeutics Relay Therapeutics (Nasdaq: RLAY) is a clinical-stage precision medicine company transforming ...

Relay Therapeutics, Inc. (RLAY) shares soared 6.7% in the last trading session to close at $8.11. The move was backed by solid volume with far more shares changing hands than in a normal session. This compares to the stock's 17.8% gain over the past four weeks. The sudden surge in the stock price can be attributed to a positive investor mindset regarding the company's pipeline progress. Relay Therapeutics is leveraging its Dynamo platform to initially focus on precision oncology. The company has several can ...

文章核心观点 - 生物科技公司Relay Therapeutics(RLAY)最近宣布进行二次公开募股,计划募集2亿美元 [1][2] - 此次发行价格为每股7美元,较最近股价大幅下跌 [2] - 此次发行将导致公司股权被稀释至少21%,这一比例较高,引发了投资者的不满 [3] 根据相关目录分别进行总结 公司情况 - Relay Therapeutics是一家专注于肿瘤治疗的生物科技公司 [1] - 公司此次二次公开募股,计划募集2亿美元资金 [2] - 此次发行将导致公司股权被稀释至少21% [3] 融资细节 - 公司计划发行约2860万股新股,每股价格7美元 [2] - 承销商团队包括高盛、TD Cowen、Stifel和美银证券 [2] - 承销商还有30天的超额配售选择权,可额外增发约430万股 [2] - 公司预计扣除费用后的净募集资金约为1.895亿美元 [2]

文章核心观点 - 公司正在进行一次规模约2亿美元的公开发行,发行2857.1429万股普通股,发行价格为每股7美元 [1] - 本次发行由高盛、TD证券、Stifel和美银美林担任联席主承销商,雷蒙德詹姆斯担任联席经理 [2] - 本次发行所得款项将用于公司的临床阶段精准医疗项目的研发 [5] 根据目录分类总结 公开发行情况 - 公司计划发行2857.1429万股普通股,并授予承销商30天内增发428.5714万股的选择权 [1] - 本次发行预计总募集资金约2亿美元,不包括承销商行使增发选择权 [1] - 本次发行由高盛、TD证券、Stifel和美银美林担任联席主承销商,雷蒙德詹姆斯担任联席经理 [2] - 本次发行将于2024年9月12日左右完成,需满足惯常的交割条件 [2] 公司概况 - 公司是一家临床阶段的精准医疗公司,致力于通过结合计算技术和实验技术来推动药物发现过程的转变 [5] - 公司的Dynamo®平台整合了多种前沿计算和实验方法,旨在开发针对之前难以治疗的蛋白靶点的小分子疗法 [5] - 公司目前主要关注在靶向肿瘤和遗传性疾病领域的小分子疗法的开发 [5]

Monday, Relay Therapeutics Inc. RLAY shared interim data for RLY-2608 from the ReDiscover study of RLY-2608 alone, in combination with fulvestrant, and in combination with fulvestrant and ribociclib or atirmociclib (Pfizer Inc's PFE selective CDK4 inhibitor). The clinical benefit rate (CBR) was 57% in heavily pretreated patients. RLY-2608 is a pan-mutant and isoformselective inhibitor of PI3Kα. Oppenheimer downgraded Relay Therapeutics, noting the upcoming data from competitors. "We believe that approved PI ...

文章核心观点 - Relay Therapeutics公司宣布其主要候选药物RLY-2608在治疗乳腺癌的早期研究中取得积极的中期数据,导致公司股价大涨52.4% [1] - RLY-2608与AstraZeneca的Faslodex联合用药,在中重度预治疗的HR+/HER2-晚期乳腺癌患者中取得了临床意义上的无进展生存期(PFS)延长 [3] - 公司称RLY-2608的独特作用机制可能为患者带来前所未有的疗效,同时毒性也明显更低 [2] 关键数据总结 - 在52例可评估患者中,RLY-2608联合Faslodex的中位PFS为9.2个月,在有激酶突变的患者中为10.3个月 [3] - 在35例可评估临床获益率(CBR)的患者中,CBR为57% [3] - 在30例可测量病灶的患者中,1/3取得部分缓解(PR),近3/4患者出现肿瘤缩小 [4] - 在15例可测量病灶且有激酶突变的患者中,超过一半取得PR [4] - 中位随访时间为7.5个月 [4] 安全性 - RLY-2608联合Faslodex的联合用药总体安全性良好,大多数不良反应轻度至中度,可控且可逆 [5] 未来发展计划 - 公司计划于2025年启动RLY-2608联合Faslodex的关键性研究,用于二线治疗HR+/HER2-晚期乳腺癌 [6] - 公司还计划于2024年四季度报告RLY-2608联合Kisqali和Faslodex三联疗法的初步安全性数据,并于2025年上半年启动剂量扩展队列 [6] - 公司还计划于2024年底启动RLY-2608联合Pfizer的atirmociclib和Faslodex的三联疗法研究 [6] - 公司还在评估RLY-2608在一线晚期乳腺癌中与Kisqali或atirmociclib的三联疗法 [6] - 公司还计划评估RLY-2608单药用于实体瘤和血管畸形 [7] 其他临床阶段候选药物 - 公司另一临床阶段候选药物lirafugratinib,FDA建议公司先提交胆管癌适应症的新药申请,再提交肿瘤无关FGFR2融合基因适应症的补充申请 [8] - 公司正在寻找lirafugratinib的全球商业化合作伙伴,以集中精力发展其他管线 [8]

CAMBRIDGE, Mass., Sept. 09, 2024 (GLOBE NEWSWIRE) -- Relay Therapeutics, Inc. (Nasdaq: RLAY), a clinical-stage precision medicine company transforming the drug discovery process by combining leading-edge computational and experimental technologies, announced today that it has commenced an underwritten public offering of $200 million of shares of its common stock. Relay Therapeutics also intends to grant the underwriters a 30-day option to purchase up to an additional fifteen percent (15%) of the shares of c ...