Agios Pharmaceuticals Inc.’s stock AGIO, +2.51% soared 19.6% early Wednesday, after the biotech announced positive results from a Phase 3 trial of a treatment for a rare blood disorder. The trial dubbed Energize sought to evaluate the company’s mitapivat therapy and met its primary endpoint of hemoglobin response in patients with non-transfusion-dependent (NTD) alpha- or beta-thalassemia. The trial also met secondary endpoints of change from baseline in FACIT-Fatigue Score and hemoglobin concentration. The ...