Shares of Wave Life Sciences (WVE) surged 74.1% on Wednesday after the company reported positive proofof-mechanism data from an ongoing early to mid-stage study of its investigational candidate, WVE-006, for alpha-1 antitrypsin deficiency (AATD), a type of genetic disorder. WVE-006 is a GalNAc-conjugated oligonucleotide that enables A-to-I RNA editing and is administered subcutaneously. Developed with Wave Life Sciences' advanced oligonucleotide chemistry platform, it is specifically designed to target lung ...