Exhibit 99.1 Contact Information Investor Relations Tel: +86 (21) 6195 9561 Email: ir@huazhu.com http://ir.huazhu.com Huazhu Group Limited Reports Fourth Quarter and Full Year 2021 Unaudited Financial Results • A total of 7,830 hotels or 753,216 hotel rooms in operation as of December 31, 2021. • Hotel turnover increased 8.3% year-over-year to RMB11.9 billion for the fourth quarter of 2021, and increased 36.4% year-overyear to RMB45.4 billion for the full year of 2021. Excluding Steigenberger Hotels AG and ...