Fourth Quarter and Full Year 2023 Financial Results & Business Update February 29, 2024 1 ©2024 KARYOPHARM THERAPEUTICS INC. On Today’s Call • Welcome Elhan Webb, CFA, Senior Vice President, Investor Relations • Overview Richard Paulson, President and Chief Executive Officer • Pipeline Update Dr. Reshma Rangwala, Chief Medical Officer • Commercial Highlights Sohanya Cheng, Chief Commercial Officer • Financial Results and Guidance Michael Mason, Chief Financial Officer • Closing Remarks Richard Paulson, Pres ...