Cabaletta Bio Reports Positive Initial Clinical Data from Phase 1/2 RESET-Myositis™ and RESET-SLE™ Trials of CABA-201
SLESuper League Enterprise(SLE) GlobeNewswire News Room·2024-06-14 14:00

– No CRS, ICANS, infections or serious adverse events observed in either of the first two patients through data cut-off of May 28, 2024 – – CABA-201 exhibited anticipated profile of CAR T cell expansion and contraction with complete B cell depletion observed in both patients by day 15 post-infusion – – Improvements in both patients' specific disease measures, consistent with academic experience of a similar 4- 1BB CD19-CAR T, suggest emerging clinical benefit with CABA-201 while discontinuing all disease-sp ...