The company had a dispiriting update to offer about an investigational drug.For the second trading session in less than a week, Roche Holding (RHHBY -6.02%) stock really took it on the chin Wednesday. Dispiriting news about its investigational obesity drug was the culprit; disseminating this, investors sold out of the pharmaceutical veteran. At the end of the day's action, Roche had lost almost 6% of its value.Obesity drug disappointsIn a meeting of the European Association for the Study of Diabetes that da ...