Fulcrum Therapeutics Upgraded: BofA Debates Pivotal Study Success For Losmapimod In Rare Genetic Muscle Disease
GENEGenetic Technologies(GENE) Benzinga·2024-09-10 02:28

BofA Securities has upgraded Fulcrum Therapeutics FULC ahead of the company’s phase 3 losmapimod readout, expected by the end of October for Facioscapulohumeral muscular dystrophy (FSHD).FSHD is a rare genetic muscle disease affecting a child’s facial muscles, shoulders, upper arms, and lower legs. These muscles weaken and shrink (atrophy).The analyst notes that although a previous pivotal study failed using the DUX4 expression endpoint, the company conducted a post-hoc analysis and designed a new study wit ...