Execution Version Exhibit 10.1 EVOGENE LTD. $7.3 Million of Ordinary Shares (par value NIS 0.02 per share) Sales Agreement March 28, 2024 Lake Street Capital Markets, LLC 920 Second Avenue South, Suite 700 Minneapolis, Minnesota 55402 Ladies and Gentlemen: Evogene Ltd., a company organized under the laws of the State of Israel (the “Company”), confirms its agreement (this “Agreement”) with Lake Street Capital Markets, LLC (the “Agent”), as follows: 1. Issuance and Sale of Shares. The Company agrees that, fr ...