Table of Contents (Mark One) ☒ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ☐TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-32597 CF INDUSTRIES HOLDINGS, INC. (Exact name of registrant as specified in its charter) Delaware 20-2697511 (State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identific ...